"This is really a study more of the delivery device than the drug or the route," he said, and it may be that using the atomizer makes the drug more bioavailable.
We performed an extensive review of the medical literature regarding sedation analgesia in children with developmental disability and neurologic disorders utilizing Pubmed.
Search terms included “sedation”, and “analgesia”, “pediatric”, “child”, “neonate”, “brain”, “developmental disabilities”, “neurologic”, “autism”, “epilepsy”, “seizure”, “stroke”, “hydrocephalus”, “traumatic brain injury”, “intracranial hemorrhage”, “hypoxia-ischemia”, and “encephalopathy” and the period of search was from 1960–2010.
The authors are pediatric neurocritical care specialists and have extensive clinical experience caring for pediatric patients with developmental disabilities and neurologic disorders and research experience in experimental animal models of pediatric neurologic injury.
Choosing a Medication Using Medication to Sedate Your Cat Using Non-Medication Sedation Methods Community Q&A There are a variety of reasons you may need to sedate your cat.
They also looked at the five-point activity scale, in which scores of either three or four are regarded as optimal, while a five means the child is not adequately sedated and one or two indicates over-sedation.
Klein and colleagues found: Klein said the study shows that intranasal midazolam can be used effectively and its increased speed of activity "could positively impact flow in a busy clinical setting, such as an emergency department." The study shows that the intranasal approach using the atomizer is "slightly" better than the other routes of administration, said Gary Fleisher, MD, of Children's Hospital Boston, who moderated the session at which the studies were presented.Cerebral hemodynamics were also studied in patients with head trauma.Patients were sedated for 6.3 /- 4.0 days (mean /- SD).With advances in health care, many children with developmental disabilities and neurologic disorders are living longer lives, and increasingly require diagnostic and therapeutic interventions.Pediatricians and pediatric subspecialists are increasing being called upon to safely sedate and provide analgesia for these children for diagnostic procedures (CT, MRI, angiogram, endoscopy, and bronchoscopy) and for therapeutic interventions (interventional radiology, intracranial injury, and emergency stabilization).Sedation is the use of a sedative or tranquilizing drug to help children relax.